Department of Defense awards $1.6 million for implantable biochip research

CLEMSON — The Department of Defense has awarded $1.6 million to the Center for Bioelectronics, Biosensors and Biochips (C3B) at Clemson University for the development of an implantable biochip

that could relay vital health information if a soldier is wounded in battle or a civilian is hurt in an accident.

The biochip, about the size of a grain of rice, could measure and relay such information as lactate and glucose levels in the event of a major hemorrhage, whether on the battlefield, at home or on the highway.

Anthony Guiseppi-Elie, C3B director and Dow Chemical Professor of Chemical and Biomolecular Engineering and professor of bioengineering says first responders to the trauma scene could inject the biochip

into the wounded victim and gather data almost immediately. The device has other long-term potential applications, such as monitoring astronauts’ vital signs during long-duration space flights and reading blood-sugar levels for diabetics.

“We now lose a large percentage of patients to bleeding, and getting vital information such as how much oxygen is in the tissue back to ER physicians and medical personnel can often mean the difference between life and death,” said Guiseppi-Elie. “Our goal is to improve the quality and expediency of care for fallen soldiers and civilian trauma victims.” The biochip also may be injected as a precaution to future traumas, he adds.

Clemson scientists have formulated a gel that mimics human tissue and reduces the chances of the body rejecting the biochip, which has been a problem in the past. The researcher predicts the biochip is five years away from human trials. The award is funded by the Department of Defense through the Peer Reviewed Medical Research Program and is a joint study with the department of molecular pathology at the University of Alabama at Birmingham and Telesensors Inc. in Knoxville, Tenn.

The Center for Bioelectronics, Biosensors and Biochips (clemson.edu/c3b/), located in the Clemson University Advanced Materials Center, operates cooperatively with industry in molecular bioanalytics and biometrology research. The center focuses on the development of platform technologies that are of mutual interest to the industrial consortium members and faculty while providing education and training for science-, technology-, engineering- and mathematics-oriented high school students, science teachers, undergraduates, graduate students and post-doctoral trainees.

Contact: Anthony Guiseppi-Elie guiseppi@clemson.edu 864-656-1712 WRITER: Susan Polowczuk, (864) 656-2063 spolowc@clemson.edu Web: Clemson University

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